名稱 | TP53 p.E349* Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10530 |
報(bào)價(jià) | ![]() |
特點(diǎn) | TP53 p.E349* Reference Standard |
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號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10530TP53 p.E349* Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10530 | |
Format | Genomic DNA |
Description | TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
Technical Data | |
DNA Change: | c.1045G>T |
AA Change | p.E349* |
Mutation type | Nonsense_Mutation |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305.4 |
Cosmic ID | COSM10770 |
Chr position(GRCh37) | chr17:7573982 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |