| 名稱(chēng) | ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10271 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | ERBB2 p.V842I Reference Standard |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- ATCC細(xì)胞株培養(yǎng)操作
- 研究揭示缺氧如何導(dǎo)致細(xì)菌引發(fā)痤瘡
- CD74-ROS1的藥靶模型+DNARNA標(biāo)準(zhǔn)品+ddPCR試劑盒
- 針對(duì)ctDNA的MRD檢測(cè)，你參與了嗎？
- 基因守護(hù)者：抑癌基因TP53
- 長(zhǎng)期研究使用的腦癌細(xì)胞系或面臨“身份危機(jī)”
- ATCC細(xì)胞的細(xì)胞破碎
- 【產(chǎn)品推介】胰高血糖素受體藥物細(xì)胞篩選模型
- ATCC細(xì)胞單純的固定液一般難以達(dá)到這些要求
- PD-1阻斷療法激活的T細(xì)胞還需依賴(lài)CD28共刺激
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10271ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10271 | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) V842I lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V842I results in increased Erbb2 (Her2) activity, downstream Mapk pathway activation, and the ability to transform cells in culture (PMID: 23220880), however in another study, V842I results in similar cell proliferation and viability levels as wild-type Erbb2 (Her2), in two different cell lines (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.2524G>A |
| AA Change | p.V842I |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000269571 |
| Cosmic ID | COSM14065 |
| Chr position(GRCh37) | chr17:37881332 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)