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基因檢測標準品 > Mutation > CBP10345EGFR p.747_753LREATSP>S Reference Standard

EGFR p.747_753LREATSP>S Reference Standard
名稱 EGFR p.747_753LREATSP>S Reference Standard
型號 CBP10345
報價
特點 EGFR p.747_753LREATSP>S Reference Standard
  • 詳細內容
CBP10345
GeneEGFR
DescriptionEGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth (PMID: 24312144). EGFR activating mutations, amplification, and overexpression are found in a variety of tumor tumors, including non-small cell lung cancer (PMID: 26609494, PMID: 30284706) and colorectal cancer (PMID: 30243897), and the EGFRvIII variant is commonly found in glioblastoma (PMID: 30201736).
  
Technical Data 
DNA Changec.2240_2257del18 TAAGAGAAGCAACATCTC>-
AA Changep.L747_P753LREATSP>S
Mutation typeDeletion - In frame
ZygosityHeterozygous
Allelic Frequency25.00%
TranscriptENST00000275493
Cosmic IDCOSM12370
Chr position(GRCh37)chr7:55242470_55242487
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10345 替換1.jpg

Storage4℃
Expiry36 months from the date of manufacture

 



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